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Induction of autoreactive B cells allows priming of autoreactive T cells

A novel mechanism for breaking T cell self tolerance is described. B cells induced to make autoantibody by immunization of mice with the non- self protein human cytochrome c can present the self protein mouse cytochrome c to autoreactive T cells in immunogenic form. This mechanism of breaking T cell...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1991
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190847/
https://ncbi.nlm.nih.gov/pubmed/1851798
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