Monocytes prime autoreactive T cells after myocardial infarction

In humans, loss of central tolerance for the cardiac self-antigen α-myosin heavy chain (α-MHC) leads to circulation of cardiac autoreactive T cells and renders the heart susceptible to autoimmune attack after acute myocardial infarction (MI). MI triggers profound tissue damage, releasing danger sign...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: DeBerge, Matthew, Yu, Shuangjin, Dehn, Shirley, Ifergan, Igal, Yeap, Xin Yi, Filipp, Mallory, Becker, Amanda, Luo, Xunrong, Miller, Stephen, Thorp, Edward B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Rapid Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985803/
https://ncbi.nlm.nih.gov/pubmed/31809213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00595.2019
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