Differential requirement for the IKKβ/NF-κB signaling module in regulating TLR versus RLR-induced type 1 IFN expression in dendritic cells()

Host innate-immune responses are tailored by cell-type to control and eradicate specific infectious agents. For example, an acute RNA virus infection can result in high-level expression of type 1 interferons (IFNs) by both conventional (cDCs) and plasmacytoid dendritic cells (pDCs), but while cDCs p...

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Main Authors: Wang, Xingyu, Wang, Junmei, Zheng, Hong, Xie, Mengyu, Hopewell, Emily L., Albrecht, Randy A., Nogusa, Shoko, García-Sastre, Adolfo, Balachandran, Siddharth, Beg, Amer A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134964/
https://ncbi.nlm.nih.gov/pubmed/25057006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400675
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