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NF-κB RelA subunit is crucial for early IFN-β expression and resistance to RNA virus replication

RNA virus infection results in expression of type 1 interferons (IFNs), especially IFN-α/β, which play a crucial role in host anti-virus responses. Type 1 IFNs are induced in a cell type-specific manner through Toll-like receptor and RIG-I-like receptor pathways, both of which activate interferon re...

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Detalhes bibliográficos
Main Authors: Wang, Junmei, Basagoudanavar, Suresh H., Wang, Xingyu, Hopewell, Emily, Albrecht, Randy, García-Sastre, Adolfo, Balachandran, Siddharth, Beg, Amer A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910841/
https://ncbi.nlm.nih.gov/pubmed/20610653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000114
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