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NF-κB RelA subunit is crucial for early IFN-β expression and resistance to RNA virus replication
RNA virus infection results in expression of type 1 interferons (IFNs), especially IFN-α/β, which play a crucial role in host anti-virus responses. Type 1 IFNs are induced in a cell type-specific manner through Toll-like receptor and RIG-I-like receptor pathways, both of which activate interferon re...
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Auteurs principaux: | , , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
2010
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2910841/ https://ncbi.nlm.nih.gov/pubmed/20610653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000114 |
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