A mechanism of suppression of TGF–β/SMAD signaling by NF-κB/RelA

A number of pathogenic and proinflammatory stimuli, and the transforming growth factor-β (TGF-β) exert opposing activities in cellular and immune responses. Here we show that the RelA subunit of nuclear factor κB (NF-κB/RelA) is necessary for the inhibition of TGF-β-induced phosphorylation, nuclear...

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Bibliographic Details
Main Authors: Bitzer, Markus, von Gersdorff, Gero, Liang, Dan, Dominguez-Rosales, Alfredo, Beg, Amer A., Rojkind, Marcos, Böttinger, Erwin P.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2000
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC316349/
https://ncbi.nlm.nih.gov/pubmed/10652273
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