Reactivation of developmentally silenced globin genes by forced chromatin looping

Distal enhancers commonly contact target promoters via chromatin looping. In erythroid cells, the locus control region (LCR) contacts β-type globin genes in a developmental stage-specific manner to stimulate transcription. Previously, we induced LCR-promoter looping by tethering the self-association...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Deng, Wulan, Rupon, Jeremy W., Krivega, Ivan, Breda, Laura, Motta, Irene, Jahn, Kristen S., Reik, Andreas, Gregory, Philip D., Rivella, Stefano, Dean, Ann, Blobel, Gerd A.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134511/
https://ncbi.nlm.nih.gov/pubmed/25126789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.05.050
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items