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MBD2 contributes to developmental silencing of the human ε-globin gene

During erythroid development the embryonic ε-globin gene becomes silenced as erythropoiesis shifts from the yolk sac to the fetal liver where γ-globin gene expression predominates. Previous studies have shown that the ε-globin gene is autonomously silenced through promoter proximal cis-acting sequen...

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Detalhes bibliográficos
Main Authors: Rupon, Jeremy W., Wang, Shou Zhen, Gnanapragasam, Merlin, Labropoulos, Stefanos, Ginder, Gordon D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062199/
https://ncbi.nlm.nih.gov/pubmed/21296012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2011.01.001
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