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MBD2 contributes to developmental silencing of the human ε-globin gene
During erythroid development the embryonic ε-globin gene becomes silenced as erythropoiesis shifts from the yolk sac to the fetal liver where γ-globin gene expression predominates. Previous studies have shown that the ε-globin gene is autonomously silenced through promoter proximal cis-acting sequen...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3062199/ https://ncbi.nlm.nih.gov/pubmed/21296012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2011.01.001 |
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