Hira-mediated H3.3 incorporation is required for DNA replication and ribosomal RNA transcription in the mouse zygote

Extensive chromatin reprogramming occurs at fertilization and is thought to be under the control of maternal factors, but the underlying mechanisms remain poorly understood. We report that maternal Hira, a chaperone for the histone variant H3.3, is required for mouse development past the zygote stag...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Lin, Chih-Jen, Koh, Fong Ming, Wong, Priscilla, Conti, Marco, Ramalho-Santos, Miguel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134436/
https://ncbi.nlm.nih.gov/pubmed/25087892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.06.022
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky