Functional activity of the H3.3 histone chaperone complex HIRA requires trimerization of the HIRA subunit

The HIRA histone chaperone complex deposits the histone variant H3.3 onto chromatin in a DNA synthesis-independent manner. It comprises three identified subunits, HIRA, UBN1 and CABIN1, however the functional oligomerization state of the complex has not been investigated. Here we use biochemical and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Ray-Gallet, Dominique, Ricketts, M. Daniel, Sato, Yukari, Gupta, Kushol, Boyarchuk, Ekaterina, Senda, Toshiya, Marmorstein, Ronen, Almouzni, Geneviève
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078998/
https://ncbi.nlm.nih.gov/pubmed/30082790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05581-y
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