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Functional activity of the H3.3 histone chaperone complex HIRA requires trimerization of the HIRA subunit
The HIRA histone chaperone complex deposits the histone variant H3.3 onto chromatin in a DNA synthesis-independent manner. It comprises three identified subunits, HIRA, UBN1 and CABIN1, however the functional oligomerization state of the complex has not been investigated. Here we use biochemical and...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6078998/ https://ncbi.nlm.nih.gov/pubmed/30082790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05581-y |
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