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HIRA dependent H3.3 deposition is required for transcriptional reprogramming following nuclear transfer to Xenopus oocytes

BACKGROUND: Nuclear reprogramming is potentially important as a route to cell replacement and drug discovery, but little is known about its mechanism. Nuclear transfer to eggs and oocytes attempts to identify the mechanism of this direct route towards reprogramming by natural components. Here we ana...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jullien, Jerome, Astrand, Carolina, Szenker, Emmanuelle, Garrett, Nigel, Almouzni, Genevieve, Gurdon, John B
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538669/
https://ncbi.nlm.nih.gov/pubmed/23102146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-5-17
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