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Hira-mediated H3.3 incorporation is required for DNA replication and ribosomal RNA transcription in the mouse zygote
Extensive chromatin reprogramming occurs at fertilization and is thought to be under the control of maternal factors, but the underlying mechanisms remain poorly understood. We report that maternal Hira, a chaperone for the histone variant H3.3, is required for mouse development past the zygote stag...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4134436/ https://ncbi.nlm.nih.gov/pubmed/25087892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.06.022 |
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