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DENR•MCT-1 Promotes Translation Reinitiation Downstream of uORFs to Control Tissue Growth
During cap-dependent eukaryotic translation initiation, ribosomes scan mRNA from the 5′ end to the first AUG start codon with favorable sequence context(1,2). For many mRNAs this AUG belongs to a short upstream open reading frame (uORF)(3), and translation of the main downstream ORF requires reiniti...
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| Auteurs principaux: | , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4134322/ https://ncbi.nlm.nih.gov/pubmed/25043021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13401 |
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