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HIV-1 Replication in Human Immune Cells Is Independent of TAR DNA Binding Protein 43 (TDP-43) Expression

The TAR DNA binding protein (TDP-43) was originally identified as a host cell factor binding to the HIV-1 LTR and thereby suppressing HIV-1 transcription and gene expression (Ou et al., J.Virol. 1995, 69(6):3584). TDP-43 is a global regulator of transcription, can influence RNA metabolism in many di...

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Detalhes bibliográficos
Main Authors: Nehls, Julia, Koppensteiner, Herwig, Brack-Werner, Ruth, Floss, Thomas, Schindler, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134290/
https://ncbi.nlm.nih.gov/pubmed/25127017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105478
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