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Accumulation of TAR DNA Binding Protein-43 (TDP-43) in Mild Cognitive Impairment and Alzheimer Disease

TAR DNA binding protein-43 (TDP-43) plays a central role in the neuropathology of frontotemporal lobar degeneration (FTLD-TDP) and amyotrophic lateral sclerosis, but the relationship between TDP-43 abnormalities and Alzheimer disease (AD) remains unclear. To determine whether TDP-43 can serve as a n...

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Autors principals: Tremblay, Cyntia, St-Amour, Isabelle, Schneider, Julie, Bennett, David A., Calon, Frédéric
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197017/
https://ncbi.nlm.nih.gov/pubmed/21865887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e31822c62cf
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