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BRAIN MURAL CELL LOSS IN THE PARIETAL CORTEX IN ALZHEIMER’S DISEASE CORRELATES WITH COGNITIVE DECLINE AND TDP-43 PATHOLOGY

AIMS: Brain mural cells (BMC), smooth muscle cells and pericytes, interact closely with endothelial cells and modulate numerous cerebrovascular functions. A loss of BMC function is suspected to play a role in the pathophysiology of Alzheimer’s Disease (AD). METHODS: BMC markers, namely smooth muscle...

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Detalhes bibliográficos
Publicado no:Neuropathol Appl Neurobiol
Main Authors: Bourassa, Philippe, Tremblay, Cyntia, Schneider, Julie A., Bennett, David A., Calon, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7739958/
https://ncbi.nlm.nih.gov/pubmed/31970820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nan.12599
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