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TDP-43 Pathology, Cognitive Decline, and Dementia in Old Age

IMPORTANCE: Cognitive decline is a leading cause of disability and death in old age but its neurobiological bases are not well understood. OBJECTIVE: To test the hypothesis that transactive response DNA-binding protein 43 (TDP-43) is related to late life cognitive decline. DESIGN: Longitudinal clini...

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Detalhes bibliográficos
Main Authors: Wilson, Robert S., Yu, Lei, Trojanowski, John Q., Chen, Er-Yun, Boyle, Patricia A., Bennett, David A., Schneider, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3830649/
https://ncbi.nlm.nih.gov/pubmed/24080705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2013.3961
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