Lack of TAR-DNA binding protein-43 (TDP-43) pathology in human prion diseases

AIMS: TAR-DNA binding protein-43 (TDP-43) is the major ubiquitinated protein in the aggregates in frontotemporal dementia with ubiquitin-positive, tau-negative inclusions and motor neurone disease. Abnormal TDP-43 immunoreactivity has also been described in Alzheimer's disease, Lewy body diseas...

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Detalhes bibliográficos
Main Authors: Isaacs, A M, Powell, C, Webb, T E, Linehan, J M, Collinge, J, Brandner, S
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607533/
https://ncbi.nlm.nih.gov/pubmed/18657254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2990.2008.00963.x
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