Tar DNA Binding Protein-43 (TDP-43) Associates with Stress Granules: Analysis of Cultured Cells and Pathological Brain Tissue

Tar DNA Binding Protein-43 (TDP-43) is a principle component of inclusions in many cases of frontotemporal lobar degeneration (FTLD-U) and amyotrophic lateral sclerosis (ALS). TDP-43 resides predominantly in the nucleus, but in affected areas of ALS and FTLD-U central nervous system, TDP-43 is aberr...

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Detalhes bibliográficos
Main Authors: Liu-Yesucevitz, Liqun, Bilgutay, Aylin, Zhang, Yong-Jie, Vanderwyde, Tara, Citro, Allison, Mehta, Tapan, Zaarur, Nava, McKee, Ann, Bowser, Robert, Sherman, Michael, Petrucelli, Leonard, Wolozin, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952586/
https://ncbi.nlm.nih.gov/pubmed/20948999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013250
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