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Tar DNA-binding protein-43 (TDP-43) regulates axon growth in vitro and in vivo()

Intracellular inclusions of the TAR-DNA binding protein 43 (TDP-43) have been reported in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD-TDP). Rare mutations in TARDBP have been linked to both ALS and FTD-TDP suggesting that TDP-43 dysfunction is mechanistic in causing disease....

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Detalhes bibliográficos
Main Authors: Tripathi, Vineeta Bhasker, Baskaran, Pranetha, Shaw, Christopher E., Guthrie, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988849/
https://ncbi.nlm.nih.gov/pubmed/24423647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.01.004
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