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Tar DNA-binding protein-43 (TDP-43) regulates axon growth in vitro and in vivo()
Intracellular inclusions of the TAR-DNA binding protein 43 (TDP-43) have been reported in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD-TDP). Rare mutations in TARDBP have been linked to both ALS and FTD-TDP suggesting that TDP-43 dysfunction is mechanistic in causing disease....
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Academic Press
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3988849/ https://ncbi.nlm.nih.gov/pubmed/24423647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.01.004 |
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