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Roles of Ataxin-2 in Pathological Cascades Mediated by TAR DNA-binding Protein 43 (TDP-43) and Fused in Sarcoma (FUS)

The RNA-binding proteins TDP-43 and Fused in Sarcoma (FUS) play central roles in neurodegeneration associated with amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Both proteins are components of messenger ribonucleoprotein (mRNP) granules and show cytoplasmic mislocalization in...

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Bibliografski detalji
Glavni autori: Nihei, Yoshihiro, Ito, Daisuke, Suzuki, Norihiro
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510829/
https://ncbi.nlm.nih.gov/pubmed/23048034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.398099
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