Characterization of Alternative Isoforms and Inclusion Body of the TAR DNA-binding Protein-43

TAR DNA-binding protein-43 (TDP-43) has been recently identified as a major component of the ubiquitinated inclusions found in frontotemporal lobar degeneration with ubiquitin-positive inclusions and in amyotrophic lateral sclerosis, diseases that are collectively termed TDP-43 proteinopathies. Seve...

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Autores principales: Nishimoto, Yoshinori, Ito, Daisuke, Yagi, Takuya, Nihei, Yoshihiro, Tsunoda, Yoshiko, Suzuki, Norihiro
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Protein Synthesis, Post-Translational Modification, and Degradation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804209/
https://ncbi.nlm.nih.gov/pubmed/19887443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.022012
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