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Crystal Structure of a Complex of NOD1 CARD and Ubiquitin

The Caspase Recruitment Domain (CARD) from the innate immune receptor NOD1 was crystallized with Ubiquitin (Ub). NOD1 CARD was present as a helix-swapped homodimer similar to other structures of NOD1 CARD, and Ub monomers formed a homodimer similar in conformation to Lys48-linked di-Ub. The interact...

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Autores principales: Ver Heul, Aaron M., Gakhar, Lokesh, Piper, Robert C., Subramanian, Ramaswamy
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134136/
https://ncbi.nlm.nih.gov/pubmed/25127239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104017
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