Ubiquitin Regulates Caspase Recruitment Domain-mediated Signaling by Nucleotide-binding Oligomerization Domain-containing Proteins NOD1 and NOD2

NOD1 and NOD2 (nucleotide-binding oligomerization domain-containing proteins) are intracellular pattern recognition receptors that activate inflammation and autophagy. These pathways rely on the caspase recruitment domains (CARDs) within the receptors, which serve as protein interaction platforms th...

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Detalhes bibliográficos
Main Authors: Ver Heul, Aaron M., Fowler, C. Andrew, Ramaswamy, S., Piper, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591598/
https://ncbi.nlm.nih.gov/pubmed/23300079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.413781
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