Ubiquitin Regulates Caspase Recruitment Domain-mediated Signaling by Nucleotide-binding Oligomerization Domain-containing Proteins NOD1 and NOD2

NOD1 and NOD2 (nucleotide-binding oligomerization domain-containing proteins) are intracellular pattern recognition receptors that activate inflammation and autophagy. These pathways rely on the caspase recruitment domains (CARDs) within the receptors, which serve as protein interaction platforms th...

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Bibliographische Detailangaben
Hauptverfasser: Ver Heul, Aaron M., Fowler, C. Andrew, Ramaswamy, S., Piper, Robert C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591598/
https://ncbi.nlm.nih.gov/pubmed/23300079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.413781
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