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WD40 Repeat Propellers Define a Ubiquitin-Binding Domain that Regulates Turnover of F Box Proteins

WD40-repeat β-propellers are found in a wide range of proteins involved in distinct biological activities. We define a large subset of WD40 β-propellers as a class of ubiquitin-binding domains. Using the β-propeller from Doa1/Ufd3 as a paradigm, we find the conserved top surface of the Doa1 β-propel...

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Autores principales: Pashkova, Natasha, Gakhar, Lokesh, Winistorfer, Stanley C., Yu, Liping, Ramaswamy, S., Piper, Robert C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266742/
https://ncbi.nlm.nih.gov/pubmed/21070969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.10.018
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