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The yeast Alix homolog, Bro1, functions as a ubiquitin receptor for protein sorting into multivesicular endosomes
Sorting of ubiquitinated membrane proteins into lumenal vesicles of multivesicular bodies is mediated by the ESCRT apparatus and accessory proteins such as Bro1, which recruits the deubiquitinating enzyme Doa4 to remove ubiquitin from cargo. Here we propose that Bro1 works as a receptor for the sele...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3755756/ https://ncbi.nlm.nih.gov/pubmed/23726974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.04.007 |
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