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DOA1/UFD3 Plays a Role in Sorting Ubiquitinated Membrane Proteins into Multivesicular Bodies

Ubiquitin (Ub) is a sorting signal that targets integral membrane proteins to the interior of the vacuole/lysosome by directing them into lumenal vesicles of multivesicular bodies (MVBs). The Vps27-Hse1 complex, which is homologous to the Hrs-STAM complex in mammalian cells, serves as a Ub-sorting r...

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Detalhes bibliográficos
Main Authors: Ren, Jihui, Pashkova, Natasha, Winistorfer, Stanley, Piper, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490793/
https://ncbi.nlm.nih.gov/pubmed/18508771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802982200
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