Plasmacytomagenesis in Eμ-v-abl transgenic mice is accelerated when apoptosis is restrained

Mice susceptible to plasma cell tumors provide a useful model for human multiple myeloma. We previously showed that mice expressing an Eµ-v-abl oncogene solely develop plasmacytomas. Here we show that loss of the proapoptotic BH3-only protein Bim or, to a lesser extent, overexpression of antiapoptot...

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Detaylı Bibliyografya
Asıl Yazarlar: Vandenberg, Cassandra J., Waring, Paul, Strasser, Andreas, Cory, Suzanne
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2014
Konular:
Lymphoid Neoplasia
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133484/
https://ncbi.nlm.nih.gov/pubmed/24986687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-570770
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