In-Cell Intrabody Selection from a Diverse Human Library Identifies C12orf4 Protein as a New Player in Rodent Mast Cell Degranulation

The high specificity of antibodies for their antigen allows a fine discrimination of target conformations and post-translational modifications, making antibodies the first choice tool to interrogate the proteome. We describe here an approach based on a large-scale intracellular expression and select...

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Detalhes bibliográficos
Main Authors: Mazuc, Elsa, Guglielmi, Laurence, Bec, Nicole, Parez, Vincent, Hahn, Chang S., Mollevi, Caroline, Parrinello, Hugues, Desvignes, Jean-Pierre, Larroque, Christian, Jupp, Ray, Dariavach, Piona, Martineau, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133367/
https://ncbi.nlm.nih.gov/pubmed/25122211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104998
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