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Mast cell degranulation breaks peripheral tolerance

Mast cells (MC) have been shown to mediate regulatory T-cell (T(reg)) dependent, peripheral allograft tolerance in both skin and cardiac transplants. Furthermore, T(reg) have been implicated in mitigating IgE mediated MC degranulation, establishing a dynamic, reciprocal relationship between MC and T...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: de Vries, Victor C., Wasiuk, Anna, Bennett, Kathryn A., Benson, Micah J., Elgueta, Raul, Waldschmidt, Thomas J., Noelle, Randolph. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808998/
https://ncbi.nlm.nih.gov/pubmed/19681828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2009.02755.x
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