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Exploring the Substrate Range of Wild-type Aminoacyl-tRNA Synthetases
We tested the substrate range of four wild-type Escherichia coli aminoacyl-tRNA synthetases (AARSs) with a library of non-standard amino acids (nsAAs). While these AARSs could discriminate efficiently against the other canonical amino acids, they were able to use many nsAAs as substrates. Our result...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4133344/ https://ncbi.nlm.nih.gov/pubmed/24890918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201402083 |
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