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Measuring, Reversing, and Modeling the Mechanical Changes Due to the Absence of Fibulin-4 in Mouse Arteries
Mice with a smooth muscle cell (SMC) specific deletion of fibulin-4 (SMKO) show decreased expression of SMC contractile genes, decreased circumferential compliance, and develop aneurysms in the ascending aorta. Neonatal administration of drugs that inhibit the angiotensin II pathway encourage expres...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4133341/ https://ncbi.nlm.nih.gov/pubmed/24526456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10237-014-0556-x |
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