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Measuring, Reversing, and Modeling the Mechanical Changes Due to the Absence of Fibulin-4 in Mouse Arteries

Mice with a smooth muscle cell (SMC) specific deletion of fibulin-4 (SMKO) show decreased expression of SMC contractile genes, decreased circumferential compliance, and develop aneurysms in the ascending aorta. Neonatal administration of drugs that inhibit the angiotensin II pathway encourage expres...

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Hlavní autoři: Le, Victoria P., Yamashiro, Yoshito, Yanagisawa, Hiromi, Wagenseil, Jessica E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133341/
https://ncbi.nlm.nih.gov/pubmed/24526456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10237-014-0556-x
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