Epidermal Growth Factor Stimulates Nuclear Factor-κB Activation and Heme Oxygenase-1 Expression via c-Src, NADPH Oxidase, PI3K, and Akt in Human Colon Cancer Cells

Previous report showed that epidermal growth factor (EGF) promotes tumor progression. Several studies demonstrated that growth factors can induce heme oxygenase (HO)-1 expression, protect against cellular injury and cancer cell proliferation. In this study, we investigated the involvement of the c-S...

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Autori principali: Lien, Gi-Shih, Wu, Ming-Shun, Bien, Mauo-Ying, Chen, Chien-Hsin, Lin, Chien-Huang, Chen, Bing-Chang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133279/
https://ncbi.nlm.nih.gov/pubmed/25122478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104891
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