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Src kinase participates in LPS-induced activation of NADPH oxidase

The production of superoxide from NADPH oxidase by macrophages in response to endotoxin (LPS) is an important innate immune response, yet it is not clear how LPS signals the activation of NADPH oxidase. The hypothesis is that LPS-induced src kinase and PI3 kinase (PI3K) facilitates the activation of...

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Detalhes bibliográficos
Main Authors: Check, Jennifer, Byrd, Christy L., Menio, Jade, Rippe, Richard A., Hines, Ian N., Wheeler, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814916/
https://ncbi.nlm.nih.gov/pubmed/19942291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2009.10.012
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