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Src kinase participates in LPS-induced activation of NADPH oxidase

The production of superoxide from NADPH oxidase by macrophages in response to endotoxin (LPS) is an important innate immune response, yet it is not clear how LPS signals the activation of NADPH oxidase. The hypothesis is that LPS-induced src kinase and PI3 kinase (PI3K) facilitates the activation of...

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Autori principali: Check, Jennifer, Byrd, Christy L., Menio, Jade, Rippe, Richard A., Hines, Ian N., Wheeler, Michael D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814916/
https://ncbi.nlm.nih.gov/pubmed/19942291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2009.10.012
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