Cigarette smoke extract upregulates heme oxygenase-1 via PKC/NADPH oxidase/ROS/PDGFR/PI3K/Akt pathway in mouse brain endothelial cells

BACKGROUND: In the brain, the inducible form of heme oxygenase (HO-1) has been recently demonstrated to exacerbate early brain injury produced by intracerebral hemorrhagic stroke which incident rate has been correlated with cigarette smoking previously. Interestingly, cigarette smoke (CS) or chemica...

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Detalhes bibliográficos
Main Authors: Shih, Ruey-Horng, Cheng, Shin-Ei, Hsiao, Li-Der, Kou, Yu Ru, Yang, Chuen-Mao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173343/
https://ncbi.nlm.nih.gov/pubmed/21861928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-104
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