Transcription regulation by inflexibility of promoter DNA in a looped complex.
The gal operon of Escherichia coli is negatively regulated by repressor binding to bipartite operators separated by 11 helical turns of DNA. Synergistic binding of repressor to separate sites on DNA results in looping, with the intervening DNA as a topologically closed domain containing the two prom...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Proc Natl Acad Sci U S A |
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| Prif Awduron: | , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
National Academy of Sciences
1995
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41332/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7638190/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.16.7327 |
| Tagiau: |
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