Transcription regulation by inflexibility of promoter DNA in a looped complex.

The gal operon of Escherichia coli is negatively regulated by repressor binding to bipartite operators separated by 11 helical turns of DNA. Synergistic binding of repressor to separate sites on DNA results in looping, with the intervening DNA as a topologically closed domain containing the two prom...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Choy, H E, Park, S W, Parrack, P, Adhya, S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41332/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7638190/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.16.7327
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