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Transcription regulation by inflexibility of promoter DNA in a looped complex.

The gal operon of Escherichia coli is negatively regulated by repressor binding to bipartite operators separated by 11 helical turns of DNA. Synergistic binding of repressor to separate sites on DNA results in looping, with the intervening DNA as a topologically closed domain containing the two prom...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:Proc Natl Acad Sci U S A
Ngā kaituhi matua: Choy, H E, Park, S W, Parrack, P, Adhya, S
Hōputu: Artigo
Reo:Inglês
I whakaputaina: National Academy of Sciences 1995
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41332/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7638190/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.16.7327
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