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Fusion between a novel Krüppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia.

We have identified a unique case of acute promyelocytic leukaemia (APL) with a t(11;17) reciprocal chromosomal translocation involving the retinoic acid receptor alpha (RAR alpha) and a previously uncharacterized zinc finger gene. As a result of this translocation, mRNAs containing the coding sequen...

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Detalhes bibliográficos
Publicado no:EMBO J
Principais autores: Chen, Z, Brand, N J, Chen, A, Chen, S J, Tong, J H, Wang, Z Y, Waxman, S, Zelent, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413318/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8384553/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05757.x
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