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Fusion between a novel Krüppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia.

We have identified a unique case of acute promyelocytic leukaemia (APL) with a t(11;17) reciprocal chromosomal translocation involving the retinoic acid receptor alpha (RAR alpha) and a previously uncharacterized zinc finger gene. As a result of this translocation, mRNAs containing the coding sequen...

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Bibliographic Details
Main Authors: Chen, Z, Brand, N J, Chen, A, Chen, S J, Tong, J H, Wang, Z Y, Waxman, S, Zelent, A
Format: Artigo
Language:Inglês
Published: 1993
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC413318/
https://ncbi.nlm.nih.gov/pubmed/8384553
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