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The Promyelocytic Leukemia Zinc Finger Protein Affects Myeloid Cell Growth, Differentiation, and Apoptosis

The promyelocytic leukemia zinc finger (PLZF) gene, which is disrupted in therapy-resistant, t(11;17)(q23;q21)-associated acute promyelocytic leukemia (APL), is expressed in immature hematopoietic cells and is down-regulated during differentiation. To determine the role of PLZF in myeloid developmen...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Shaknovich, Rita, Yeyati, Patricia L., Ivins, Sarah, Melnick, Ari, Lempert, Cheryl, Waxman, Samuel, Zelent, Arthur, Licht, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109138/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9710637/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.9.5533
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