The Promyelocytic Leukemia Zinc Finger Protein Affects Myeloid Cell Growth, Differentiation, and Apoptosis

The promyelocytic leukemia zinc finger (PLZF) gene, which is disrupted in therapy-resistant, t(11;17)(q23;q21)-associated acute promyelocytic leukemia (APL), is expressed in immature hematopoietic cells and is down-regulated during differentiation. To determine the role of PLZF in myeloid developmen...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Shaknovich, Rita, Yeyati, Patricia L., Ivins, Sarah, Melnick, Ari, Lempert, Cheryl, Waxman, Samuel, Zelent, Arthur, Licht, Jonathan D.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1998
Schlagworte:	Cell Growth and Development
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109138/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9710637/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.9.5533
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