The Promyelocytic Leukemia Zinc Finger Protein Affects Myeloid Cell Growth, Differentiation, and Apoptosis

The promyelocytic leukemia zinc finger (PLZF) gene, which is disrupted in therapy-resistant, t(11;17)(q23;q21)-associated acute promyelocytic leukemia (APL), is expressed in immature hematopoietic cells and is down-regulated during differentiation. To determine the role of PLZF in myeloid developmen...

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Hauptverfasser: Shaknovich, Rita, Yeyati, Patricia L., Ivins, Sarah, Melnick, Ari, Lempert, Cheryl, Waxman, Samuel, Zelent, Arthur, Licht, Jonathan D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
Schlagworte:
Cell Growth and Development
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC109138/
https://ncbi.nlm.nih.gov/pubmed/9710637
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