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Loss of GPx2 increases apoptosis, mitosis, and GPx1 expression in the intestine of mice

Localization of GPx2, the gastrointestinal form of glutathione peroxidases (GPx), in the intestinal crypt epithelium points to a specific but so far unknown function of this particular GPx. Therefore, consequences of a GPx2 knockout were tested in mice fed a selenium-restricted, -adequate or -supple...

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Main Authors: Florian, Simone, Krehl, Susanne, Loewinger, Maria, Kipp, Anna, Banning, Antje, Esworthy, Steven, Chu, Fong-Fong, Brigelius-Flohé, Regina
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132893/
https://ncbi.nlm.nih.gov/pubmed/20828612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.08.029
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