Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply

Chronic inflammation and selenium deficiency are considered as risk factors for colon cancer. The protective effect of selenium might be mediated by specific selenoproteins, such as glutathione peroxidases (GPx). GPx-1 and -2 double knockout, but not single knockout mice, spontaneously develop ileoc...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Krehl, Susanne, Loewinger, Maria, Florian, Simone, Kipp, Anna P., Banning, Antje, Wessjohann, Ludger A., Brauer, Martin N., Iori, Renato, Esworthy, Robert S., Chu, Fong-Fong, Brigelius-Flohé, Regina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2012
Aiheet:
Inflammation, Microenvironment and Prevention
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291858/
https://ncbi.nlm.nih.gov/pubmed/22180572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr288
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