Epigenetic Modulation of Intestinal Cholesterol Transporter Niemann-Pick C1-like 1 (NPC1L1) Gene Expression by DNA Methylation

Intestinal NPC1L1 transporter is essential for cholesterol absorption and the maintenance of cholesterol homeostasis in the body. NPC1L1 is differentially expressed along the gastrointestinal tract with very low levels in the colon as compared with the small intestine. This study was undertaken to e...

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Главные авторы: Malhotra, Pooja, Soni, Vinay, Kumar, Anoop, Anbazhagan, Arivarasu N., Dudeja, Amish, Saksena, Seema, Gill, Ravinder K., Dudeja, Pradeep K., Alrefai, Waddah A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2014
Предметы:
Gene Regulation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132811/
https://ncbi.nlm.nih.gov/pubmed/24904062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.546283
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