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Mechanisms of Niemann-Pick type C1 Like 1 protein degradation in intestinal epithelial cells

Intestinal Niemann-Pick C1 Like 1 (NPC1L1) protein plays a key role in cholesterol absorption. A decrease in NPC1L1 expression has been implicated in lowering plasma cholesterol and mitigating the risk for coronary heart disease. Little is known about the mechanisms responsible for NPC1L1 protein de...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Physiol Cell Physiol
Prif Awduron: Malhotra, Pooja, Soni, Vinay, Yamanashi, Yoshihide, Takada, Tappei, Suzuki, Hiroshi, Gill, Ravinder K., Saksena, Seema, Dudeja, Pradeep K., Alrefai, Waddah A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482670/
https://ncbi.nlm.nih.gov/pubmed/30789754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00465.2018
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