Epigenetic Modulation of Intestinal Cholesterol Transporter Niemann-Pick C1-like 1 (NPC1L1) Gene Expression by DNA Methylation

Intestinal NPC1L1 transporter is essential for cholesterol absorption and the maintenance of cholesterol homeostasis in the body. NPC1L1 is differentially expressed along the gastrointestinal tract with very low levels in the colon as compared with the small intestine. This study was undertaken to e...

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Main Authors: Malhotra, Pooja, Soni, Vinay, Kumar, Anoop, Anbazhagan, Arivarasu N., Dudeja, Amish, Saksena, Seema, Gill, Ravinder K., Dudeja, Pradeep K., Alrefai, Waddah A.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2014
主題:
Gene Regulation
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132811/
https://ncbi.nlm.nih.gov/pubmed/24904062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.546283
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